Samantha Rousell.

William J. Sandborn, M.D ., Subrata Ghosh, M.D., Julian Panes, M.D., Ivana Vranic, Ph.D., Chinyu Su, M.D., Samantha Rousell, M.Sc., and Wojciech Niezychowski, M.D. For the Study A3921063 Investigators: Tofacitinib, an Oral Janus Kinase Inhibitor, in Active Ulcerative Colitis Ulcerative colitis is certainly a chronic inflammatory disease of the colon.1,2 Patients have intermittent disease flares interspersed with periods of remission.4-6 These agents aren’t effective universally, and some have already been associated with serious toxic effects.7 Additional remedies are needed.

Merino, M.D., Sunita K. Agarwal, Ph.D., Lisa Zhang, Ph.D., Maggie Cam, Ph.D., Dhaval Patel, M.D., and Electron Kebebew, M.D.: Brief Record: Germline HABP2 Mutation Leading to Familial Nonmedullary Thyroid Cancer Thyroid malignancy is common in the usa, with an increase of than 62,000 instances projected in 2015. Thyroid cancers of follicular-cell origin take into account more than 95 percent of most cases of thyroid cancers, with the remaining cancers originating from parafollicular cells . Familial nonmedullary thyroid cancers, which makes up about 3 to 9 percent of most cases of thyroid cancer, has an autosomal dominant design of inheritance.2,3 Nonsyndromic familial nonmedullary thyroid malignancy makes up about more than 95 percent of most cases of familial nonmedullary thyroid tumor.2 Most situations of familial nonmedullary thyroid cancers are papillary thyroid cancers, which is the most common kind of thyroid cancer.