However, the solid correlation between CTX-II and both the incidence and severity of OA was been shown to be independent of age, sex, and body mass index. This is the first huge follow-up study in which the use of CTX-II as a biomarker for cartilage degradation and disease progression offers been investigated, emphasizes the team’s leading researcher and spokesperson, M. Reijman, MSc. Predicated on the outcomes, we conclude that the CTX-II focus is markedly associated with the prevalence and progression of OA of the knee and hip, and these associations are independent of known risk elements for radiographic OA.You can also add natural almonds for a great snack every once in awhile to guarantee the body has the protein it needs to function. Step #4 Progressive Strength Training Most women have already been told ‘lift light weights for toning – you don’t desire to bulk with weighty weights’. Sorry girls, this is actually false! The ONLY way to tone up is to strength train heavier than you’re familiar with lifting. Light weights are excellent for building endurance in the muscles but very ineffective at toning you. Every month you have to modification the reps to ensure you’re body gets surprised.